🧠 MRCOG Part 1 — Overview

Purpose:
Part 1 tests your basic and applied sciences knowledge relevant to Obstetrics & Gynaecology. It ensures you understand the scientific foundations that underpin clinical practice.


🧾 Exam Format (Structure)

ComponentDetails
Exam TypeComputer-based (CBT)
Duration2 papers (each 2.5 hours) on the same day
Total Questions200 SBAs (Single Best Answers)
Question StyleEach SBA has 5 options (A–E), only one best answer
Marking1 mark per question; no negative marking
LocationPearson VUE test centres (worldwide)

📘 Paper Breakdown

Paper 1 – Basic Sciences (100 Questions)

Covers the fundamentals related to O&G:

  • Anatomy (Pelvic, Reproductive, Surgical)

  • Physiology (Reproductive, Endocrine, Cardiovascular, Renal, etc.)

  • Biochemistry

  • Biophysics

  • Embryology

  • Genetics

  • Biostatistics & Epidemiology (basic level)

  • Pharmacology (relevant to pregnancy)

  • Pathology (principles)


Paper 2 – Applied Basic Sciences (100 Questions)

Applies scientific knowledge to clinical O&G:

  • Reproductive endocrinology & physiology of pregnancy

  • Fertilization, implantation, early development

  • Fetal physiology & growth

  • Labour mechanisms

  • Placental function

  • Pathophysiology of obstetric & gynaecological disorders

  • Pharmacological agents used in O&G

  • Anatomy related to surgical procedures

  • Screening, statistics & interpretation of data


📚 Core Areas Covered

DomainExamples
AnatomyPelvic floor, blood supply, ureteric relations
PhysiologyMenstrual cycle, hormones, pregnancy changes
PathologyInflammation, neoplasia, reproductive cancers
PharmacologyOxytocin, prostaglandins, antibiotics in pregnancy
GeneticsChromosomal abnormalities, inheritance patterns
EmbryologyDevelopment of genital tract, implantation
BiostatisticsSensitivity, specificity, p-values
Evidence-based medicineStudy designs, bias, clinical trials

💡 Passing Standard

  • The pass mark is set using the Angoff method (based on expected performance of a borderline candidate).

  • Each paper is marked separately, but both must be passed in the same sitting to clear Part 1.


🧩 Recommended Reading


🎯 Tips for Preparation

  • Focus on conceptual understanding, not just memorization.

  • Use question banks (like MedisPrep, PassMRCOG, or RCOG Learning).

  • Revise reproductive physiology and anatomy in detail — highly tested.

  • Practice timed mock SBAs regularly.

  • Keep revisiting statistics — often underestimated but high-yield.

🗓️ 6-Week MRCOG Part 1 Study Plan

📍Week 1 – Anatomy & Embryology

Focus: Female pelvis, perineum, urogenital tract, embryological development
Topics

  • Pelvic bones, muscles, vessels, nerves

  • Uterine and ovarian anatomy

  • Ureteric course and injuries

  • Development of reproductive tract, genitalia, placenta

  • Congenital anomalies (e.g. Müllerian defects)

Resources:

  • Netter’s Atlas (selected plates), MRCOG Part 1: Essential Revision Guide Ch 1–2

  • MedisPrep Anatomy Flashcards

  • GTG No. 37a illustrations for venous pathways

Tasks:

  • 50 SBA practice / day

  • Label pelvic diagrams

  • Mini-test Sunday


📍Week 2 – Physiology & Reproductive Endocrinology

Focus: Menstrual cycle, hypothalamo–pituitary–ovarian axis, pregnancy physiology
Topics

  • Hormone regulation and feedback loops

  • Puberty, menopause

  • Fertilisation, implantation

  • Maternal cardiovascular, renal, respiratory adaptations

  • Fetal growth & amniotic fluid

Resources:

  • Guyton & Hall summaries (selected chapters)

  • RCOG syllabus → Section 2 “Reproductive Physiology”

  • MedisPrep mock set 2


📍Week 3 – Biochemistry & Cell Biology

Focus: Cellular metabolism and molecular genetics
Topics

  • Cell structure, cell cycle

  • Protein synthesis, enzymes, hormones

  • Maternal–fetal metabolism (glucose, lipids)

  • Vitamins & trace elements

  • DNA replication, chromosomal abnormalities

Resources:

  • Lippincott’s Illustrated Biochemistry quick review

  • GTG 68 – Genetic Screening (for clinical links)


📍Week 4 – Pathology & Microbiology

Focus: Mechanisms of disease
Topics

  • Inflammation, necrosis, neoplasia

  • Gynae cancers (cell types & spread)

  • Immunology of pregnancy

  • Microbiology of genital tract infections (BV, chlamydia, GBS)

  • TORCH infections

Resources:

  • Robbins Basic Pathology concise notes

  • GTG No. 64 b (Management of sepsis)

  • MedisPrep SBA Pathology module


📍Week 5 – Pharmacology & Therapeutics

Focus: Drug action and safety in pregnancy
Topics

  • Pharmacokinetics & dynamics

  • Teratogenic drugs (ACE inhibitors, warfarin, etc.)

  • Tocolytics, uterotonics, antihypertensives, antibiotics

  • Drug transfer across placenta & breastfeeding safety

Resources:

  • Rang & Dale Pharmacology review

  • BNF + GTG 37b (anticoagulation in pregnancy)

Tasks:

  • Drug tables & contraindications flashcards

  • 60 SBAs (Pharmacology only)


📍Week 6 – Biostatistics, Evidence & Integration

Focus: Data interpretation + full syllabus revision
Topics

  • Sensitivity, specificity, predictive values

  • Confidence intervals, p-values, study design

  • Screening principles (RCOG GTG 8 & 13)

  • Integrate physiology + pathology through clinical SBAs

Resources:

  • Medical Statistics Made Easy

  • RCOG “Applied Basic Sciences” syllabus checklist

Final Week Tasks:

  • 3 Full-length timed mocks (200 Q each)

  • Review wrong answers

  • Focus on weak domains


🧩 Weekly Routine Template

DayFocusTasks
Mon–FriStudy 2 topics/day2 × 1-h reading blocks + 50 SBAs
SatMock test (100 Qs)Review explanations
SunConcept revisionSummarise notes + rest half-day

📚 Essential Resources

  • RCOG official syllabus: “MRCOG Part 1 Curriculum 2024”

  • Books:

    • MRCOG Part 1: Your Essential Revision Guide

    • One for All MRCOG Part 1

    • Get Through MRCOG Part 1 (for SBAs)

  • Online: